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Author

Lanxiang Wu

2 papers indexed here

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Open access Oct 2026

Multimodal analysis identifies a fibroblast subtype enriched in EGFR-mutant NSCLC and its spatial niches

The tumor microenvironment (TME) in non-small cell lung cancer (NSCLC) exhibits heterogeneity across distinct oncogenic driver mutations, but whether specific stromal states are shaped by these mutations and how they influence tumor progression and therapy response remains inadequately understood. We integ...

Xiao Yang, Xiao-Qing Wang, Min Zhang et al. · 0 citations
Review Jul 2026

STING agonists in tumor therapy: structural pharmacology, determinants of productive activation, and barrier-matched therapeutic strategies.

The cyclic GMP-AMP synthase-stimulator of interferon genes pathway is a central innate immune axis that connects cytosolic DNA sensing with type I interferon production, dendritic-cell activation, and downstream T-cell priming. These functions have positioned stimulator of interferon genes (STING) as an attractive ther...

Chenyi Li, Lanxiang Wu · 0 citations

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