Review
Open access
Jul 2026
Targeting lysosome-dependent cell death in cancer: towards therapeutic strategies
Lysosomes serve as central degradative hubs in cells, playing critical roles in maintaining protein homeostasis, clearing damaged organelles, and regulating metabolic signaling. Tumor cells heavily rely on lysosomal functions during proliferation, invasion, and drug resistance, a dependency that concurrently endows the...
Yang Li, Jiajie Feng, Xinzhu Dong et al.
· Biomarker Research · 0 citations