Open access
Jul 2026
Loss of Atp8a2 drives neurodegeneration through the dysregulation of spatiotemporal phosphatidylserine externalization in mature neurons
Mapping the spatiotemporal dynamics of PS exposure in mature hippocampal neurons under physiological and pathological conditions using time-lapse imaging reveals specific PS externalization hotspots at dendritic branching points, presenting a potential target for neuroprotective strategies in neurodegeneration.
Adriana Schneider, Alexandra B. Merkel, Nunzio Perta et al.
· Cell Death and Disease · 0 citations