Case Report: Staged alteplase administration under VA-ECMO support for high-risk pulmonary embolism with severe thrombocytopenia
High-risk pulmonary embolism (PE) with severe thrombocytopenia creates competing reperfusion and bleeding risks. A 28-year-old man presented with obstructive shock and central pulmonary arterial filling defects. The last documented platelet count before alteplase was 21 × 10⁹/L; platelet transfusion intervened, and the...