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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Le Li

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2 papers indexed here

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Open access Aug 2026

Molecular dynamics analysis of a docking-derived baicalein–PPARγ ligand-binding-domain model suggests a pocket-associated AF-2-anchor-silent ensemble

Baicalein was examined in a selected docking-derived peroxisome proliferator-activated receptor γ (PPARγ) ligand-binding-domain (LBD) model to test whether pocket association, local helix 12 (H12) organization, and canonical activation function-2 (AF-2) anchoring were coupled under the sampled simulation conditions. Be...

Xing-Yuan Kou, Ping Wu, Zhuo Liu et al. · 0 citations
Open access Sep 2026

Integrated microarray-based and single-cell transcriptomic analyses reveal cell adhesion-related fibrotic remodeling signatures in heart failure

Background Heart failure (HF) is characterized by impaired cardiac pumping function and progressive remodeling. Cell adhesion is essential for tissue integrity and the regulation of inflammation and fibrosis. This study aimed to identify key cell adhesion-related genes (CARGs) and explore their roles in HF. Methods HF-...

Shun Zhang, Le Li, Zuo-Hua Li et al. · 0 citations

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