Le Zhang

A Bispecific Nanobridge Derived from Immunogenic Tumor Membranes Restores Dendritic Cell–T Cell Crosstalk for Enhanced Solid Tumor Immunotherapy

In solid tumors, communication between dendritic cells (DCs) and T cells is impaired by poor immune infiltration and lack of physical contact, limiting current immunotherapies. Here, we develop a bispecific immune-bridging platform (NVMB) to address these limitations. NVMB consists of tumor cell membrane-derived nano...