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Open access Oct 2026

Disorganized bone collagen fibers in early-stage type 2 diabetes mellitus and its association with adipose tissue redistribution

Type 2 diabetes mellitus (T2DM) compromises bone quality and biomechanical integrity, driven by impaired microstructure, suppressed turnover, and collagen abnormalities. Crucially, this fragility occurs despite normal bone mineral density and may initiate early in the disease, underscoring the need for timely skeletal...

Ying Liu, Qi-Jie Meng, Shuo Chen et al. · 0 citations
Open access Sep 2026

CT-based age-related trabecular redistribution in the proximal femur and its association with fracture patterns in elderly individuals with and without diabetes

Proximal femoral fractures are the most common fall-related fractures in the elderly. In our clinical work, we observed a phenomenon of trabecular redistribution in the proximal femur of older individuals. To investigate the distribution of bone trabeculae (compression and tension trabeculae) in the proximal femur, the...

Shuo Chen, Xue-Feng Ma, Qiang-Ting Meng et al. · 0 citations

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