Open access
Jul 2026
CircBRWD3 promotes non-small cell lung cancer progression through enhancing the stability of TRIM25 to increase p53 ubiquitin degradation and upregulating SPTBN2.
A tumor oncogenic function of circBRWD3 is uncovered in NSCLC through the regulation of TRIM25 protein stability and miR-135a-5p/miR-135b-5p/SPTBN2 axis.
Yan-Hua Zhu, Yue-Feng He, Mei Xiao et al.
· Cell Death and Disease · 0 citations