Somatotropic axis drives bone turnover heterogeneity independently of gonadotropin synergy in girls with central precocious puberty
Background The classic paradigm of somatotropic-gonadal axis synergy in pubertal bone acquisition lacks validation in central precocious puberty (CPP), and the driver of the significant bone turnover marker (BTM) heterogeneity in this population is unknown. Objective To investigate the independent and potential synergi...