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Open access Sep 2026

Comprehensive Risk Factor Control Attenuates Excess Cardiovascular Risk in Rheumatoid Arthritis: A Prospective Cohort Study.

OBJECTIVE Rheumatoid arthritis (RA) confers substantially elevated cardiovascular disease (CVD) risk. We quantified the association between joint risk factor control and incident CVD among RA patients and examined modification by genetic susceptibility. METHODS In this prospective UK Biobank cohort, 4,426 RA patients...

Hong-Xuan Fan, Xiao-Yu Zi, Tian-Jiao Li et al. · 0 citations
Open access Aug 2026

Frailty, social disconnection, metabolomic signatures, and incident peripheral artery disease in type 2 diabetes: a prospective cohort study

Frailty, loneliness, and social isolation remained associated with incident PAD after mutual adjustment among individuals with T2DM, and the potential relevance of physical vulnerability and social disconnection to PAD risk is supported, while the metabolomic findings require external validation.

Li Zhao, Xin-Rui Xue, Tian-Jiao Li et al. · 0 citations

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