The crosstalk between sequestosome 1 and heme oxygenase-1 in regulating autophagy/oxidative stress in bovine mammary epithelial cells.
Bovine mastitis severely compromises dairy cattle health, primarily through oxidative stress and dysregulated autophagy in bovine mammary epithelial cells (BMECs), ultimately impairing lactation performance. While heme oxygenase-1 (HO-1) is well-established as a critical regulator of oxidative stress and autophagy, its...