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Lei Wang

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Jul 2026

CoAff-DTI: Fine-grained drug-target interaction prediction using pre-trained language models and affinity-guided mechanisms

CoAff-DTI is proposed, an end-to-end deep learning framework designed to enhance multi-scale interaction modeling for DTI prediction and consistently outperforms state-of-the-art methods on multiple benchmark datasets.

Jia Peng, Xiaoyu Liu, Lei Wang et al. · 0 citations