Early plasma cell-free DNA and monocyte human leukocyte antigen-DR expression for predicting 28-day mortality in sepsis: A single-center prospective cohort study with internal validation
Objective Sepsis remains associated with substantial short-term mortality, and conventional severity indicators may not fully capture biological heterogeneity related to tissue injury, inflammation, and immune suppression. This study evaluated whether early plasma cell-free DNA and monocyte human leukocyte antigen-DR (...