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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Lei Zheng

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Open access Aug 2026

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

A novel inducible ON‐switch CAR design that leverages plant hormone signaling components to achieve controllable T cell activation allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.

Hongxiang Zeng, Lei Zheng, Rongkun Tao et al. · 0 citations

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