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Open access Sep 2026

DNMT1 is associated with QDPR downregulation and chemotherapy response in lung adenocarcinoma

In lung adenocarcinoma (LUAD), DNA methylation-mediated gene silencing may contribute to tumor initiation, progression, and heterogeneity in treatment response. However, the key methyltransferases involved and their therapeutic potential have not been systematically characterized. This study aimed to address three majo...

Lyubo Wang, Gui-Cai Liang, Lei Zhu et al. · 0 citations
Open access Sep 2026

Clinical Subtype Stratification Reveals Gut Microbial Alterations, Candidate Markers, and Co-Occurrence Network Remodeling in Coronary Artery Disease

Although gut microbiota dysbiosis is associated with coronary artery disease (CAD), its dynamic alterations across distinct clinical stages remain largely unexplored. This study aimed to identify stage-specific microbial biomarkers across the CAD spectrum. We analyzed 16S rRNA sequencing data from 306 subjects, includi...

Pei-Qi Yan, Chen Tian, Lei Zhu et al. · 0 citations

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