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Open access Oct 2026

SU5, a Stable Auraptene Analog, Ameliorates Metabolic Dysfunction-Associated Steatohepatitis Through Modulation of the FXR Signaling Pathway.

Metabolic Dysfunction-Associated Steatohepatitis (MASH), a metabolic liver disease severely threatening public health, is characterized by hepatic steatosis, inflammatory infiltration, and fibrotic progression. Currently, there is still a lack of specific therapeutic approaches for MASH in clinical practice. Auraptene...

Fen Wen, Jing Chen, Lei Zhu et al. · 0 citations
Open access Oct 2026

Exogenous hydrogen sulfide alleviates cerebral ischemia/reperfusion injury via inhibiting RIPK1-mediated neuronal necroptosis and ROS overaccumulation

Exogenous H2S or Nec-1 exhibited significant neuroprotective effects against cerebral I/R injury by suppressing RIPK1-mediated neuronal necroptosis and inhibiting ROS, providing a novel theoretical basis for the clinical management of ischemic stroke.

Chuan-Jiang Huang, Hao Shang, Zhi-Hao Fang et al. · 0 citations

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