Transcriptomic and proteomic signatures following AS03-adjuvanted Influenza A/H7N9 vaccine
Introduction Vaccines targeting avian influenza virus A/H7N9 are poorly immunogenic. While the immune responses can be improved with oil-in-water emulsion adjuvants such as Adjuvant System 03 (AS03), the cellular mechanisms underpinning the adjuvant effect are incompletely characterized and poorly understood. Methods W...