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Author

Leon E. Hugo

1 paper indexed here

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Open access Aug 2026

Sequence Homology and Tissue Tropism Determine Superinfection Exclusion of Zika virus in Aedes aegypti Mediated by an insect-specific Binjari-Zika Virus Chimera

It is demonstrated that incorporation of Zika virus prM and E proteins into the ISF backbone enhances infection of the mosquito midgut following oral exposure, which enables direct inhibition of ZIKV infection after a subsequent infectious blood meal, and defines a replication-dependent, tissue-specific mechanism of ISF-mediated protection.

Wessel Willemsen, Alyssa J. Peterson, Marleen Henkens et al. · 0 citations

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