In Vitro Activity of Aztreonam–Avibactam, Cefiderocol, and Conventional Antimicrobials Against Metallo-β-Lactamase-Producing Gram-Negative Urinary Isolates: A Systematic Review and Local Single-Center Retrospective Evaluation in a Tertiary Care Hospital (2016–2025) and Evaluation of Novel Agents (20
Background: Metallo-β-lactamase (MBL)-producing Gram-negative bacteria represent one of the greatest therapeutic challenges in contemporary clinical microbiology because of their extensive antimicrobial resistance and the limited availability of effective treatment options. Aztreonam–avibactam and cefiderocol have emer...