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Author

Lev Levintov

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Open access Oct 2026

Nonadditive Conformational Effects of tRNA Core Modifications

Post-transcriptional modifications are known to regulate the structure and function of tRNA molecules. Compared to modifications in the anticodon region, the mechanistic effects of modifications in the core region of tRNA remain poorly understood. Using all-atom molecular dynamics (MD) simulations on yeast tRNAPhe, w...

Teddy E. Amissah, Lev Levintov, Harish Vashisth · 0 citations
Open access Oct 2026

Conformational Dynamics of Phase-Separating Methacrylated Carbohydrates

Polysaccharide-based materials, particularly dextran (Dex) derivatives, have emerged as versatile platforms for biomedical and materials science applications primarily due to their tunable chemical functionality and intrinsic biocompatibility. Native Dex is a highly hydrophilic molecule and does not inherently exhibi...

Lev Levintov, Erfan Moaseri, Nazgol Behbahani et al. · 0 citations
Open access Jul 2026

Thermophysical Properties of a tRNA Isodecoder

The computed C p profile of the unmodified tRNA displayed a well-defined peak consistent with experimentally reported C p thermograms for various tRNAs, and the effects of different monovalent ions, distinct interatomic potentials, and varying melting temperature values on the key thermophysical properties of the tRNA...

Lev Levintov, Esteban A. Orellana, Harish Vashisth · 0 citations

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