Author

Lewis J. Williams

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Open access Oct 2026

A human-induced pluripotent stem cell-derived spheroid model to investigate myelin injury and repair.

There are no currently approved therapies that promote new myelin formation after myelin damage, which can, in part, be attributed to a lack of reliable systems that can reproducibly model these processes. Here we engineered a human iPSC-derived spheroid model enriched with mature, myelinating oligodendrocytes and func...

Shwathy Ramesan, Joel Mason, Sandeep S. Kumar et al. · Nature Neuroscience · 0 citations

Open access Sep 2026

Host immune biomarkers associated with infection risk after CAR T-cell therapy.

BACKGROUND Infection is the leading cause of non-relapse mortality after CAR-T therapy, yet individual risk prediction remains challenging. This exploratory study evaluated immune correlates of infection and other treatment-emergent adverse events in patients with diffuse large B-cell lymphoma (DLBCL) receiving CAR-T....

Gemma K. Reynolds, Lewis J. Williams, Göknur Giner et al. · Journal of Infection · 0 citations