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Author

Li-Hua Guo

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Review Open access Aug 2026

Progress and challenges in exploring the pathogenesis of depressive disorders via RNA sequencing

Current evidence indicates that immune-inflammatory activation, impaired synaptic plasticity, and mitochondrial energy metabolism dysfunction constitute shared core pathological mechanisms across these disorders, validating classical pathogenic hypotheses at the molecular level.

Bo-Yu Zhang, Shi-Zhong Zheng, Li-Hua Guo et al. · 0 citations

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