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Author

Li-Juan Hu

2 papers indexed here

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Review Open access Sep 2026

Isocitrate Dehydrogenase (IDH) Mutations in Hematological Malignancies: Epidemiology, Mechanisms, and Therapeutic Strategies

Isocitrate dehydrogenase (IDH) mutation is an important molecular abnormality in hematological malignancies, occurring widely in various disease types such as acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and myelodysplastic syndrome (MDS). IDH mutations promote the occurrence and progression of h...

Jin-Kun Xu, H. Bai, Li-Juan Hu · 0 citations
Open access Aug 2026

Bone marrow mesenchymal stem cells are functionally remodeled after complete remission of acute myeloid leukemia

Abstract Background and Objectives Acute myeloid leukemia (AML) is a type of hematological malignancy, induces the normal bone marrow (BM) microenvironment to supporting AML cells. Although previous work revealed that functional remodeling of BM endothelial progenitor cells after complete remission (CR), as another imp...

Zhi-wei Zhang, Zhenkun Wang, Xin-Yan Zhang et al. · 0 citations

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