Review
Open access
Oct 2026
Periostin within the tumor microenvironment: molecular insights and immunomodulatory roles in cancer
Periostin, also known as osteoblast-specific factor 2 (OSF-2), is a secreted matricellular protein with pleiotropic functions in both physiological and pathological processes. While it contributes to tissue repair, bone remodeling, and cardiovascular and respiratory homeostasis, accumulating evidence highlights its c...
Yong-Xin Zhao, Yan Yu, Shuang-Da Li et al.
· Frontiers in Immunology · 0 citations