Author

Li-Juan Zhao

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Sep 2026

Discovery of Novel Quinazoline-Based KDM1A Inhibitors as Dual Inducers of Ferroptosis and Apoptosis in Esophageal Cancer

In a KYSE510 xenograft model, oral administration of JH-1 significantly suppressed tumor growth without obvious toxicity and validate the quinazoline scaffold for epigenetic cancer therapy.

Li-Juan Zhao, Rui Yu, Ying Liu et al. · Journal of Medicinal Chemist... · 0 citations

Review Open access Aug 2026

Exosomes—nano-messengers in tumors: capturing techniques, birth codes, and functional deciphering

This review delves into exosome isolation techniques, the regulatory mechanisms underlying their biogenesis and secretion, and their dual roles in cancer progression, metastasis, and tumor immunity, concluding with a discussion of the challenges and future directions in their clinical translation.

Ying-Ying Li, Ya Gao, Yan-Hong Wang et al. · Frontiers in Cell and Develo... · 0 citations