RNAi-Mediated Knockdown of the Sodium Channel Auxiliary Subunit TipE Increases Pyrethroid-Associated Mortality and Reveals Metabolic Transcriptional Responses in Megalurothrips usitatus
Background: The bean flower thrips, Megalurothrips usitatus, is a destructive agricultural pest with increasing resistance to pyrethroid insecticides. Most mechanistic studies emphasize mutations in the pore-forming voltage-gated sodium channels α-subunit, whereas the contribution of insect-specific sodium-channel auxi...