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Open access
Sep 2026
Night-to-night sleep variability and all-cause and cardiovascular mortality: a prospective cohort study with a complementary in vitro circadian-disruption experiment
Irregular sleep–wake patterns may disrupt circadian rhythms, but the dose–response relationship between night-to-night sleep variability and mortality and the association of sleep onset variability with death remain unclear. Using 4–7 valid days of wrist accelerometer data, including ≥1 weekend day, from 7,6...
Jing Bai, Peng Chen, Chao Cui et al.
· Frontiers in Medicine · 0 citations