Author

Li-Mei Guan

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Open access Oct 2026

Exploring biomarkers related to branched-chain amino acid metabolism in childhood obesity based on transcriptomics and experimental verification

Childhood obesity (CO) is a complex chronic disease driven by environmental, behavioral, and genetic factors. Dysregulation of branched-chain amino acid metabolism (BCAAM) contributes to CO development, highlighting the need to identify reliable biomarkers for diagnosis and treatment. Biomarkers associated with BCAAM...

Hui-Jie Zhang, Yi Lei, Li-Mei Guan et al. · Scientific Reports · 0 citations

Open access Sep 2026

Global burdens of diabetes mellitus in adolescents from 1990 to 2023 and future trend predictions: An analysis of the Global Burden of Disease study 2023

Background Adolescent diabetes mellitus (DM) constitutes a significant global public health challenge. This study seeks to quantify the burden of DM in adolescents aged 10–19 years from 1990 to 2023 and to forecast trends in incidence, prevalence, mortality, and disability-adjusted life years (DALYs) through 2040. Meth...

Xin-Yi Qiu, Li-Mei Guan, Hui Liu · PLoS ONE · 0 citations