Li-Nan Duan

Multiple co-occurring genetic variants in an elderly patient with Liddle’s-like syndrome: a case report and literature review

Liddle syndrome (LS) is a rare autosomal dominant condition classically defined by early-onset hypertension, hypokalemia, metabolic alkalosis, and a suppressed renin-aldosterone profile, primarily driven by gain-of-function mutations in the SCNN1A , SCNN1B , or SCNN1G genes encoding the epithelial sodium...