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Li-Ping Chen

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Open access Oct 2026

LARP1-mediated stabilization of CD73 mRNA promotes immune escape in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is characterized by limited therapeutic options and frequent immune escape, while the molecular mechanisms linking tumor-intrinsic programs with antitumor immunity remain incompletely understood. LARP1 was identified through integrative analysis of TNBC transcriptomic d...

Xia Qiu, Ji-Ying Shen, Ying-Xin Guan et al. · 0 citations
Open access 2027

Integration of network pharmacology and metabolomics to elucidate Qi-Xiong-Qu-Yu decoction mitigates myocardial ischemia via regulating Nrf2/ROS/MAPK signaling

Background: Qi-Xiong-Qu-Yu decoction (QXD) is an empirical herbal formula developed for the clinical treatment of ischemic heart disease. Methods: Isoproterenol (ISO) was used to establish a rat model of myocardial ischemia, and the effects of QXD were evaluated. The chemical profile of QXD was identified using UPLC-Q-...

Li-Ping Chen, Hang-Hang Gou, Cheng-Hu He et al. · 0 citations

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