Integrated AUF-UPLC-MS and fraction-activity correlation to identify COX-2-targeted constituents of Shaoyao Gancao decoction
Shaoyao Gancao Decoction (SGD), a classical multi-ingredient herbal formula, exerts potent anti-inflammatory and anti-rheumatoid arthritis effects against rheumatoid arthritis (RA). Existing cellular experiments have proven that SGD can downregulate Cyclooxygenase-2 (COX-2) expression in inflammatory macrophages, imp...