Review
Open access
Aug 2026
Mitochondrial dysfunction-driven ferroptosis in cerebral ischemia-reperfusion injury: Mechanisms and therapeutic strategies (Review)
A multidimensional pathological network composed of multiple mitochondrial abnormalities, including mitochondrial reactive oxygen species bursts, Ca2+ overload and disruption of the mitochondrial quality control system, synergistically amplifies lipid peroxidation and drives neuronal ferroptosis across the pathophysiological progression of CIRI.
Jian-Hui Li, An-Nan Liu, Wei Gao et al.
· Molecular Medicine Reports · 0 citations