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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Li-Qiang An

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4 papers indexed here

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Open access Sep 2026

Gut Microbiota-Derived Butyrate Induces Trained Immunity in Intestinal Macrophages to Potentiate Antitumor Immunity

The gut microbiota metabolite butyrate plays an important role in maintaining intestinal immune homeostasis, but it’s still unclear whether it can induce trained immunity in intestinal macrophages and thus affect anti-tumor immune responses. This study aimed to investigate the ability of butyrate to induce trained immu...

Gang Liu, Jia Wang, Li-Qiang An · 1 citation
Open access Sep 2026

Targeting Mitochondrial Metabolic Reprogramming: Reversing CD8⁺ T Cell Exhaustion and Improving Cancer Immunotherapy Response

This study explores the reversal effect of targeting mitochondrial metabolic reprogramming on CD8⁺ T cell exhaustion within the tumor microenvironment and its synergistic mechanism when combined with immune checkpoint blockade therapy. B16-OVA melanoma and LLC lung cancer tumor-bearing mouse models were established. Us...

Gang Liu, Jia Wang, A. Vasiukevich et al. · 0 citations
Open access Sep 2026

CRISPR Screen and Single-Cell Multi-Omics Identify a Novel Immune Checkpoint on Tumor-Infiltrating Regulatory T Cells

Tumor infiltration regulatory T cells (Tregs) mediate immune escape by highly expressing multiple inhibitory receptors, which is one of the key factors in resistance to existing immune checkpoint inhibitors. However, systematic screening of Treg-specific immune checkpoints within tumors remains lacking. This study aims...

Gang Liu, Jia Wang, Li-Qiang An · 0 citations
Open access Sep 2026

Mitochondrial DNA Sensing Reshapes the Tumor Immune Microenvironment via Cooperative cGAS-STING Activation and Ferroptosis

Abnormal release of mitochondrial DNA (mtDNA) and innate immune sensing play key roles in tumor immune regulation, but how they work together with ferroptosis is still unclear. This study aims to clarify the molecular mechanism of how mtDNA reshapes the tumor immune microenvironment in coordination with ferroptosis thr...

Gang Liu, Jia Wang, Li-Qiang An · 1 citation

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