Li-Qiang Shi

Hastatoside ameliorates alcohol-associated liver disease, potentially involving ATF4-regulated PANoptosis signaling cascades.

This study aimed to elucidate the therapeutic efficacy of Hastatoside (Has) against alcohol‑associated liver disease (ALD) and characterize the molecular mechanisms underlying its hepatoprotective effects. For in vivo studies, mice were fed a Lieber‑DeCarli ethanol diet for 28 days to establish ALD models, followed by...