Small-molecule photosensitizer for enhanced antiangiogenesis and immunosuppressive tumor microenvironment reprogramming in anti-metastatic photodynamic therapy.
T-Pc-mediated photodynamic therapy (PDT) significantly suppressed primary tumor growth and pulmonary metastasis, which could be attributed to its combined vascular disruption effect, and the subsequent remodeling of the immunosuppressive tumor microenvironment.