Li-Sha Nie

Subvoxel quantitative susceptibility mapping reveals distinct susceptibility patterns and clinical associations of juxtacortical paramagnetic rims in multiple sclerosis.

BACKGROUND Juxtacortical paramagnetic rims (JPRs) have emerged as potential biomarkers of cortical pathology in multiple sclerosis (MS), yet their susceptibility characteristics and clinical significance remain unclear. OBJECTIVES To characterize the heterogeneity of cortical lesions (CLs), with a particular focus on...

Neurovascular dysfunction in cerebral small vessel disease: impact on cognition and depression using arterial spin labeling and resting-state fMRI

NODDI-derived U-Fiber MRI Markers for Risk Stratification of Progression Independent of Relapse Activity in Relapsing-remitting Multiple Sclerosis.

Advanced diffusion MRI-derived U-fiber metrics may complement clinical measures for exploratory PIRA risk stratification in RRMS and warrant validation in independent multicenter cohorts.