IRAK1BP1 negatively regulated innate immune response via NF-κB signal pathway in blunt snout bream (Megalobrama amblycephala).
Results indicated that maIRAK1BP1 played an important role in mediating host innate immune response to pathogen invasion, and disclosed the involvement of maIRAK1BP1 in NF-κB-mediated production of proinflammatory cytokines, which provided foundational insights into the conserved role of IRAK1BP1 in teleost immune regulation.