Sep 2026
CTR1-mediated copper uptake orchestrates metabolic-epigenetic regulation of pathogenic TH17 cells in autoimmune disease
Lucile Noyer, Li-Wei Wang, Miki Jishage et al.
· bioRxiv · 0 citations
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Jul 2026
Copper Shapes T Cell Metabolism and Epigenetics to Drive Pathogenic Th17 Cell Function in Autoimmunity 2259915
Pathogenic T helper 17 (pTh17) cells are a subset of CD4+ T cells driving autoimmune diseases including multiple sclerosis (MS). To identify transporters controlling pTh17 cells, we conducted an in vivo shRNA-based forward genetic screen using the experimental autoimmune encephalomyelitis (EAE) model of MS...
Lucile Noyer, Liwei Wang, Miki Jishage et al.
· Journal of Immunology · 0 citations