Carbon–bromine bond cleavage is a fundamental step in many chemical transformations. Over the past two decades, the reductive cleavage of C(Ar)─Br bonds (via a stepwise pathway) and C(alkyl)─Br bonds (via a concerted pathway) has been extensively studied. In contrast, the cleavage of the C(alkynyl)─Br bond remains unre...
Jun-Ya Wang, Xiao-Zhou Wang, Pui Ying Choy et al.· Advancement of science· 0 citations
A copper-catalyzed regioselective borylative cyclization of chloromethyl butenylsilanes with bis(pinacolato)diboron has been reported. The reaction proceeds via an endo-selective cyclization to deliver 4-silacyclohexyl boronates, which undergo a two-step oxidation sequence to afford 4-silacyclohexanones. DFT calculatio...
Chen-Li Jin, Ting Wu, Rong-Jun Shi et al.· Organic Letters· 0 citations
Stereodivergent synthesis to access multiple isomers of polysubstituted alkenes represents an elegant strategy. While significant progress has been made in accessing di- and trisubstituted alkenes, the stereodivergent synthesis of both Z and E isomers of tetrasubstituted alkenes remains limited. Here, we disclose cobal...
Zi-Wei Luo, Ming Huang, Yue-Ning Pan et al.· Organic Letters· 0 citations
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