Li Xiao

From TLS architecture to functional immune niches: division of labor among CAFs, HEVs, and antigen-presenting cells in cancer immunotherapy

Tertiary lymphoid structures (TLSs) are associated with antitumor immunity and have prompted efforts to induce lymphoid organization within tumors. The central interpretive problem is whether the resulting tissue changes contribute to treatment benefit or accompany effects mediated by other cells. Building on establish...