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Review Open access Sep 2026

A compound heterozygous combination of SLC34A2 variants in pulmonary alveolar microlithiasis: A case report and literature review

Pulmonary Alveolar Microlithiasis (PAM) is a rare hereditary lung disorder characterized by the intra-alveolar deposition of calcium phosphate microliths. It is primarily familial and follows an autosomal recessive inheritance pattern, with no significant gender disparity in incidence. In its early stages, PAM is often...

Zhi-Zhen Zou, Ping Mei, Li-Xu Yan et al. · 0 citations
Aug 2026

FUS inactivation promotes leptomeningeal metastasis of lung cancer through the up-regulation of CD36.

The prognosis of non-small cell lung cancer (NSCLC) with leptomeningeal metastasis (LM) is dismal. The regulators of LM progression remain elusive, thus impeding effective clinical intervention. Here, we performed in vivo genome-wide CRISPR-based screens and found that fused in sarcoma (FUS) ablation promoted LM in bot...

Shou-Heng Lin, Kai Yin, M. Zheng et al. · 0 citations

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