Author

Liyan Zhao

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Open access Oct 2026

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

ABSTRACT Glioblastoma (GBM) remains one of the most lethal malignancies because durable tumor control is constrained by limited brain‐tumor drug exposure, metabolic plasticity, stem‐like tumor states, and an immunosuppressive microenvironment. We developed apolipoprotein B fragment‐decorated nanoparticles co‐loaded wit...

Yi-Ning Jiang, Wen-Zhuo Yang, Wen-Ting Cheng et al. · Advancement of science · 0 citations

Open access Sep 2026

Hypoxia confers ferroptosis resistance in glioma cells via HIF-1α/SREBP1-mediated regulation of lipid metabolism

The role of the HIF-1α-SREBP1-FASN/SCD1 signaling axis in ferroptosis regulation in glioma is systematically elucidated, providing important theoretical foundations and experimental support for developing HIF-1α-targeted ferroptosis therapies.

Zhong-Jun Shen, Yao Zhao, Ming-Bo Jia et al. · Journal of Lipid Research · 0 citations