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Open access Sep 2026

Use of Composite Priors for Assurance of Sequential Therapy Trials: Practical Experiences Using Binary Endpoint Data

Accurately calculating assurance can play an important role in quantifying the confidence in the success of a clinical trial. Formulation of prior distributions and the use of assurance can therefore play a vital part in drug development planning and decision‐making. Although approaches in developing priors and calcula...

Jonathan Wright, Li Ye · 0 citations

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