Decoding Mesenchymal Stem Cell Heterogeneity by Single-Cell Transcriptomics: From Molecular Insights to Harnessing Heterogeneity for Precision Therapy of Musculoskeletal Degenerative Diseases
Mesenchymal stem/stromal cells (MSCs) hold great promise for treating musculoskeletal degenerative diseases such as osteoarthritis, sarcopenia, and osteoporosis, yet their clinical translation is severely hindered by cellular heterogeneity. This review systematically examines the multidimensional origins of MSCs hetero...