Author

Li-Ying Zhan

2 papers indexed here

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Open access Sep 2026

Guanine promotes acute lung injury by repressing H3K27me3 in sepsis.

The findings reveal that circulating G6PD promotes lung injury by rewiring purine metabolism and remodeling the epigenetic profile in sepsis, shedding light on the critical role of EVs as a pro-inflammatory signal and targeting G6PD for future sepsis diagnosis and treatment.

Chao-Qun Wang, Hui-Juan Wang, Yue-Yu Kong et al. · Protein & Cell · 0 citations

Sep 2026

Ginsenoside alleviates sepsis related acute lung injury by inhibiting the destruction of alveolar epithelial barrier mediated by EVs secreted by alveolar macrophages.

Sepsis-associated acute lung injury (SALI) is a critical complication of sepsis, characterized by alveolar epithelial barrier disruption and excessive inflammation, which contributes substantially to morbidity and mortality. The present study investigates the protective effects of ginsenoside Rb1 on SALI and elucidates...

Ming Hao, Yun-Yan Zhang, Liu Chen et al. · International Immunopharmaco... · 0 citations