Li-Yun Gong

Circular RNA Fgfr2 suppresses hepatic fibrosis through the miR-1941-5p/DDAH1 axis and modulates oxidative stress- and autophagy-related signaling.

Hepatic fibrosis is driven by sustained activation of hepatic stellate cells (HSCs), but the post-transcriptional mechanisms that couple pathogen-induced liver injury to HSC activation remain poorly understood. Here, we profiled circular RNAs (circRNAs) in primary HSCs from Schistosoma japonicum-infected mice and ident...