Neuroinflammation and astrocytic ferroptosis form a self-reinforcing vicious cycle across multiple neurological disorders, constituting a core pathological mechanism driving the progression of neurodegeneration, stroke, epilepsy, autoimmune encephalopathy. Initial neuroinflammation activates microglia to release pro-in...
Li Zhang, Di-Jun Wang, Wei-Qi Wang et al.· Biomedical Reports· 0 citations
INTRODUCTION
Ischemic stroke remains a leading cause of disability and mortality worldwide. Current neuroprotective treatments predominantly target neurons and fail to address the complex post-ischemic cell death cascades in astrocytes, the most abundant glial cells in the central nervous system, whose multimodal Progr...
Li Zhang, Yong-Lan Ruan· Current Neurovascular Resear...· 0 citations
While ncRNAs represent promising candidates for migraine biomarkers and therapeutic targets, their clinical translation requires rigorous validation beyond current proof-of-concept studies.
Li Zhang, Di-Jun Wang, Wei-Qi Wang et al.· Frontiers in Neurology· 0 citations
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