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Lian-Feng Li

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Open access Aug 2026

A Recombinant Pseudorabies Virus Expressing Classical Swine Fever Virus (CSFV) E2 Protein Confers Complete Protection Against Lethal CSFV Challenge via Needle-Free Immunization

Background/Objectives: Classical swine fever (CSF) and pseudorabies (PR), caused by classical swine fever virus (CSFV) and pseudorabies virus (PRV) respectively, are economically significant viral diseases worldwide that severely compromise swine health and constrain international trade. Previously, we generated a reco...

Ruojia Huang, Qiang Yang, Cao-Yuan Ma et al. · 0 citations
Open access Aug 2026

A CHO-Expressed Pseudorabies Virus gD Subunit Vaccine Elicits Potent Neutralizing Antibodies and Confers Complete Protection Against Lethal Challenge in Mice

Background/Objectives: Pseudorabies virus (PRV) variant strains have caused widespread outbreaks in China since 2011, and currently available vaccines provide suboptimal protection. Glycoprotein D (gD), the principal target of virus-neutralizing antibodies, represents a promising antigen for subunit vaccine development...

Caoyuan Ma, Jia Li, Xin Song et al. · 0 citations
Aug 2026

[Construction and characterization of a stable Cas9-expressing monoclonal WSL cell line].

The generation of a WSL-Cas9 monoclonal cell line with high CRISPR/Cas9 editing efficiency, stable proliferation, and permissiveness for robust ASFV replication is reported, providing a reliable platform for future genome-wide functional screening to systematically identify host factors governing ASFV entry.

Meng Yao, Tianlong Li, Bin Sun et al. · 0 citations

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