Open access
Sep 2026
ALDOC promotes cardiomyocyte proliferation and heart regeneration via suppressing RBM39-ubiquitination
The adult mammalian heart exhibits a severely limited regenerative capacity, making myocardial injury a major clinical challenge. Enhancing cardiomyocyte proliferation has emerged as a promising strategy for cardiac repair and regeneration. In this study, we identify aldolase C (ALDOC), a key glycolytic enzyme, whose...
Si-Bo Wang, Ting Zhu, Liuhua Zhou et al.
· Cell Death & Disease · 0 citations