Dysregulation of three-dimensional (3D) genome architecture is a hallmark of cancer, yet the mechanisms by which its disruption drives tumorigenesis remain incompletely understood. Here, we demonstrated that SMAD4 regulated 3D genome organization through its canonical transcription factor activity by directly binding c...
Ya-Ping Xu, Xin-Yan Han, Jun-Ming Li et al.· Oncogene· 0 citations
A comprehensive and up-to-date overview of AI-driven PTM site prediction across more than ten PTM classes, covering single-PTM site prediction, multiple-PTM site prediction, inter-site crosstalk prediction, and functional prediction of modification sites is provided.
Jia-Yi Ran, Xiao-Han Zhang, Yun-Ze Wang et al.· Genomics, Proteomics & Bioin...· 0 citations
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